Brian R. Dorn, Ph.D.

Dr. Dorn practices intellectual property law with an emphasis on patent prosecution and opinion work. He advises clients regarding patent filing strategy, clearance searching, patentability searching, validity analysis, and infringement analysis. Dr. Dorn's practice is concentrated in biotechnology and pharmaceuticals. His experience includes prosecuting patents and providing regarding stem cells, therapeutic peptides, humanized antibodies, small molecule pharmaceuticals and therapeutic uses, pharmaceutical delivery systems, antimicrobials, diagnostic and immuno-assays, phage display systems, microarrays, transgenic animals, and medical device coatings.

Dr. Dorn's practice also includes international work. He works with patent attorneys in other countries to obtain patents in those specific countries and in the U.S. for non-U.S. applicants.

Dr. Dorn also serves on the Advisory Board for the University of Minnesota's Joint Degree Program in Law, Health & the Life Sciences. As a member of the Advisory Board, Dr. Dorn is among a group of attorneys, physicians, researchers and policy makers who counsel the program and mentor joint degree students. Additionally, Dr. Dorn serves on the Board of Directors of the American Israel Chamber of Commerce of Minnesota.

Education

Legal Presentations  

"Biosimilars Law in Flux: An Update" to be presented at Life Science Association of Manitoba, Winnipeg, MB, October 13, 2011.

"Exploiting New Opportunities in Biologics and Subsequent Entry Biologics" at the Canadian Institute's 9^th Annual Forum on Pharma Patents, Toronto, ON, November 4, 2010.

"Reviewing Significant Cases in Canada and the United States and Their Impact on Patent Prosecution and Litigation" at the Canadian Institute's 9^th Annual Forum on Pharma Patents, Toronto, ON, November 4, 2010.

"Biosimilars" presented with Katherine M. Kowalchyk at Minnesota Intellectual Property Law Association (October 21, 2010).

"The Patentability of DNA Claims after Myriad," presented with Katherine M. Kowalchyk, Minnesota CLE webinar, June 28, 2010. webcast

"Biosimilars" presented with Katherine M. Kowalchyk at Biosimilars: Current Laws and Trends in Legislation, Minneapolis, MN, February 26, 2010. 

 "Are Genes Patentable?" presented with Katherine M. Kowalchyk and Mark T. Skoog at American Bar Association Intellectual Property Roundtable, Minneapolis, MN, February 4, 2010.

Legal Writings

Brian R. Dorn, Biosimilars Law in Limbo: An Update on Biosimilars and Politics, FDLI Update, July/August 2011. View

Co-author of amicus curiae brief on behalf of Kane Biotech Inc. in Assn. for Molecular Pathology, et al. v. USPTO, et al. (ACLU v. Myriad Genetics) ("gene patenting" case), October 29, 2010. view 

Brian R. Dorn and Katherine M. Kowalchyk, Biosimilars: Recently Enacted Legislation for an Approval Pathway, The Edge, April 2010.

Brian R. Dorn and Katherine M. Kowalchyk. Wyeth v. Kappos: the New Calculation for Patent Term Adjustment, 2010 Emerging Issues 4862, February 2010. view

Brian R. Dorn Diagnosing Bilski. Bio•IT World. (January/February 2010). view

Brian R. Dorn, Providing Real Value to Clients (Chapter 4), M. Kraham (ed.), Life Sciences Law Client Strategies: Leading Lawyers on Intellectual Property Management, Disputes, and Other Key Business Considerations (Inside the Minds). Aspatore Books. Boston, Massachusetts (2007). abstract

Anthony R. Zeuli and Brian R. Dorn, Perspectives on the Law: Intellectual Property, Bench & Bar, April 2004, at 11.

Anthony R. Zeuli and Brian R. Dorn, Perspectives on the Law: Intellectual Property, Bench & Bar, July 2002, at 33.

Brian R. Dorn, Chakrabarty in the Era of Genomics, 6 Journal of Technology Law & Policy 101 (2001). view

Roundtables 

"Medical Technology Roundtable" hosted by U.S. Representative Erik Paulsen and Senator Amy Klobuchar, Eden Prairie, MN, July 8, 2010.

"U.S.-Israel Biotechnology Business Roundtable" at the Biotechnology Industry Organization (BIO) 2010, Chicago, IL, May 5, 2010 (hosted by the U.S.-Israel Science & Technology Foundation) (commented on the recently enacted biosimilars legislation).

Quoted

"Dispute over DNA Patnet Could Upend Biotech Industry." MedCity News (November 8, 2010) (Commenting on The Myriad "gene patenting" case (Ass. of Molecular Pathology v. USPTO) before the Federal circiut and possible impact on the biotech industry).  

"Supreme Court Gives Some Relief, But Leaves Open Questions For Dx Patents," The Gray Sheet 36(27): 3 (July 5, 2010) (commenting on diagnostic methods in view of the U.S. Supreme Court's Bilski decision). view

"Bilski v. Kappos: High Court Opinion Gives Some Relief, but Leaves Open Questions for Dx Patents," The Gray Sheet (June 29, 2010) (commenting on diagnostic methods in view of the U.S. Supreme Court's Bilski decision). view

Scientific Publications 

Jandik, K.A., Bélanger, M., Low, S.L., Dorn B.R., Yang, M.C.K., and Progulske-Fox, A. Invasive differences among Porphyromonas gingivalis strains from healthy and disease periodontal sites. Journal of Periodontal Research. 43: 524-530 (2008). view

Kozarov, E.V., Dorn, B.R., Raynald, M., Shelburne, C.E., Dunn, Jr., W.A., and Progulske-Fox, A. Human Atherosclerotic Plaque Contains Viable Invasive Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis. Arteriosclerosis, Thrombosis, and Vascular Biology. 25: e17-e18 (2005). view

Dunn, W.A., Jr., B.R. Dorn, and A. Progulske-Fox. Trafficking of bacterial pathogens to autophagosomes (Chapter 19), p. 233-240. D.J. Klionsky (ed.), Autophagy. Landes Bioscience. Georgetown, Texas (2003). abstract

Dorn, B.R., Harris, L.J., Wujick, C.T., Vertucci, F.J, and Progulske-Fox, A. Porphyromonas endodontalis in vitro invasion of vascular cells. International Journal of Endodontics. 35: 366-371 (2002). abstract

Dorn, B.R., Dunn, William A., Jr., and Progulske-Fox, A. Bacterial interactions with the autophagic pathway. Cellular Microbiology. 4: 1-10 (2002). (Cover Article). view

Dorn, B.R., Dunn, William A., Jr., and Progulske-Fox, A. Porphyromonas gingivalis traffics to autophagosomes in human coronary artery endothelial cells. Infection and Immunity. 69: 5698-5708 (2001). view

Dorn, B.R., Burks, J.N., Seifert, K.N., and Progulske-Fox, A. Invasion of endothelial and epithelial cells by strains of Porphyromonas gingivalis. FEMS Microbiology Letters. 187: 139-144 (2000). view

Progulske-Fox, A., Kozarov, E., Dorn, B., Dunn, W., Burks, J., and Wu, Y. Virulence factors of Porphyromonas gingivalis and invasion of cells of the cardiovascular system. Journal of Periodontal Research. 34: 393-399 (1999). abstract

Dorn, B.R., Dunn, William A., Jr., and Progulske-Fox, A. Invasion of human coronary artery cells by periodontal pathogens. Infection and Immunity. 67: 5792-5798 (1999). Cited in ASM News Journal Highlights, 2000, 66: 29. view

Dorn, B.R., Leung, K.-P., and Progulske-Fox, A. Invasion of human oral epithelial cells by Prevotella intermedia. Infection and Immunity. 66: 6054-6057 (1998). view

Scientific Presentations

Dorn, B.R., Dunn, Jr., W.A., and Progulske-Fox, A. (2001). Porphyromonas gingivalis persistence and exiting in endothelial cells. Abstract presented at the General Meeting of the American Society for Microbiology. Orlando, Florida.

Dorn, B. R., Dunn, Jr., W. A., and Progulske-Fox, A. (2000) Intracellular trafficking of Porphyromonas gingivalis in endothelial cells. Oral session presented at the University of Florida Medical Guild Graduate Student Research Competition. Gainesville, FL (First place in the University of Florida College of Medicine's Microbiology/Immunology Concentration; Fifth in the University of Florida College of Medicine's Interdisciplinary Program).

Dorn, B.R., Kozarov, E.V., Harris, L., Whitlock, J.A., and Progulske-Fox, A. (2000). Both hagA and hagB Hemagglutinins of Porphyromonas gingivalis Act as Adhesins for Invasion of HCAEC. Abstract presented at the General Meeting of the American Society for Microbiology. Los Angeles, California.

Dorn, B.R., Burks, J.N., and Progulske-Fox, A. (2000). Porphyromonas gingivalis FimA expression is not sufficient for invasion. Abstract presented at the General Session and Exhibition of the International Association for Dental Research. Washington, D.C.

Dorn, B. R., Dunn, Jr., W. A., and Progulske-Fox, A. (2000) Intracellular trafficking of Porphyromonas gingivalis in endothelial cells. Abstract presented at the General Session and Exhibition of the International Association for Dental Research. Washington, D.C. (Finalist in both the International and the American Associations for Dental Research's Warner-Lambert Hatton graduate student competitions).

Progulske-Fox, A., Kozarov, E., Dorn, B., Dunn, W., Burks, J., and Wu, Y. (1999). Virulence factors of Porphyromonas gingivalis and invasion of cells of the cardiovascular system. Symposium presented at the International Conference on Periodontal Research. Göteborg, Sweden.

Dorn, B.R., Dunn, Jr., W.A., and Progulske-Fox, A. (1999) Porphyromonas gingivalis traffics to the autophagic pathway after invasion of HCAEC. Abstract presented at the American Society for Microbiology's Conference on A Cell Biology Approach to Microbial Pathogenesis. Portland, Oregon.

Dorn, B.R., Kozarov, E.V., and Progulske-Fox, A. (1999) Invasion of HUVEC and KB cells by Porphyromonas gingivalis. Abstract presented at the General Session and Exhibition of the International Association for Dental Research. Vancouver, Canada.

Whitlock, J.A., Dorn, B.R., Burks, J.N., Kozarov, E.V., and Progulske-Fox, A. (1998). Porphyromonas gingivalis hag B/C hemagglutinin mutant exhibits reduced invasion of human oral epithelial cells. Abstract presented at the General Session and Exhibition of the International Association for Dental Research. Nice, France.

Dorn, B.R. and Progulske-Fox, A. (1998) Invasion of human coronary artery cells by Porphyromonas gingivalis. Oral session presented at the General Session and Exhibition of the International Association for Dental Research. Nice, France.

Dorn, B.R. and Progulske-Fox, A. (1998). Invasion of human coronary artery endothelial cells and coronary smooth muscle cells by periodontal pathogens. Abstract presented at the Conference on Microbes, Haemostasis and Vascular Biology co-sponsored by the American Society for Microbiology, Texas A&M University, and the World Health Organization. Galveston, Texas.

Press Releases

"Brian Dorn Travels to Israel with Congressman Erik Paulsen," Press Release view