Colorado, 2011
U.S. District Court for the District of Colorado, 2011
U.S. District Court for the Eastern District of Texas, 2010
Minnesota State Bar, 2008
U.S. District Court for the District of Minnesota, 2008

Professional Affiliations

Denver Bar Association

Publications & Speaking

Fletcher RJ, Bishop BE, Leon RP, Sclafani RA, Ogata CM, Chen XS. The structure and function of MCM from archaeal M. Thermoautotrophicum. Nature Structure Biology. 2003 Mar; 10(3): 160-67. Cover Story.

Sclafani RA, Fletcher RJ, Chen XS. (2004) Two heads are better than one: regulation of DNA replication by hexameric helicases. Genes and Development. 2004 Sep 1; 18(17): 2039-45.

Fletcher RJ, Shen JP, Gomez-Llorente Y, Marten CS, Carazo JM, Chen XS. Double hexamer disruption and biochemical activities of Methanobacterium thermoautotrophicum MCM. J Biol Chem. 2005 Dec 23; 280(51): 42405-10.

Gomez-Llorente Y, Fletcher RJ, Chen XS, Carazo JM, Sam Martin C, Polymorphism and double hexamer structure in the archaeal minichromosome maintenance (MCM) helicase from Methanobacterium thermoau-totrophicum. J Biol Chem. 2005 Dec 9; 280(49): 40909-15.

Fletcher RJ, Chen XS. Biochemical activities of the BOB1 mutant in Methanobacterium thermoautotrophicum MCM. Biochemistry. 2006 Jan 17; 45(2): 462-7.

Burdo JR, Martin J. Menzies SL, Dolan KG, Romano MA, Fletcher RJ, Garrick MD, Garrick LM, Conner JR. Cellular distribution of iron in the brain of the Belgrade rat. Neuroscience. 1999. 93(3): 1189-96.

With a Ph.D. in biochemistry, Dr. Ryan Fletcher brings a deep understanding of technology to his clients' patent needs. He enjoys working with companies who develop forward-thinking technology, helping them build and protect that technology as a foundation of the company.

Ryan is an attorney in the Denver office whose practice covers all areas of intellectual property law, with an emphasis on patent litigation, opinions and assisting in patent prosecution.

Prior to joining Merchant and Gould, Ryan studied the structure and function of minichromosome maintenance (MCM) proteins at the University of Colorado. Ryan solved and published the x-ray crystallography structure for the n-terminal portion of an archaeal MCM protein, revealing a double hexamer formation. While at the University of Buffalo, Ryan studied the cellular distribution of iron in the brain of the Belgrade rat.

Ryan has represented low-income inventors pro bono in patent applications. He enjoys road biking, mountain biking, and skiing.